Appendix A
Non-Pharmacological Interventions for Post-Discharge Care in Heart Failure
Appendix A
Search strategy
| #Search History | Results |
|---|---|
| 1 discharge planning.mp. or exp Patient Discharge/ | 32632 |
| 2 case management.mp. or exp Patient Care Planning/ or exp Case Management/ |
92238 |
| 3 patient readmission.mp. | 9266 |
| 4 Aftercare/ | 12568 |
| 5 Continuity of Patient Care/ | 20217 |
| 6 Patient Transfer/ | 8094 |
| 7 Post discharg$.tw. | 2180 |
| 8 Postdischarg$.tw. | 2738 |
| 9 Post hospital$.tw. | 1061 |
| 10 Posthospital$.tw. | 1047 |
| 11Predischarg$.tw. | 1810 |
| 12 Pre discharg$.tw. | 496 |
| 13 Patient$ discharg$.tw. | 7039 |
| 14Discharg$.ti. | 24270 |
| 15 ((readmission$ or early or premature or care or medication or destination or decision or decid$ or support$ or prepar$ or process$ or plan$ or system$) adj6 discharg$).tw. |
25564 |
| 16 or/1-15 | 194133 |
| 17 exp Heart Failure, Congestive/ or exp Cardiac Output, Low/ or Heart failure.mp. |
167913 |
| 18 16 and 17 | 3660 |
| 19 limit 18 to english language | 3394 |
| 20 limit 19 to “all adult (19 plus years)” | 2544 |
| 21 randomized controlled trial.pt. | 688706 |
| 22 controlled clinical trial.pt. | 221479 |
| 23 Randomized controlled trials/ | 125964 |
| 24 random allocation/ | 112192 |
| 25 double-blind method/ | 252902 |
| 26 single-blind method/ | 27409 |
| 27 clinical trial.pt. | 157319 |
| 28 (random$ or rct).tw. | 900347 |
| 29 controlled clinical trials/ | 39157 |
| 30 (clin$ adj trial$).tw. | 222839 |
| 31 ((singl$ or doubl$ or trebl$ or Tripl$) adj (blind$ or mask$)).tw. |
275580 |
| 32 exp PLACEBOS/ | 70143 |
| 33 placebo$.tw. | 288743 |
| 34 cross-over studies/ | 53318 |
| 35 evaluation studies/ | 214252 |
| 36 or/21-35 | 2048057 |
| 37 20 and 36 | 684 |
| 38 animal/ not (animal/ and human/) | 3078777 |
| 39 37 not 38 | 684 |
| 40 limit 39 to comment and (letter or editorial).pt. | 1 |
| 41 limit 39 to (addresses or bibliography or biography or case reports or congresses or consensus development conference or consensus development conference, nih or dictionary or directory or editorial or festschrift or government publications or interview or lectures or legal cases or legislation or news or newspaper article or patient education handout or periodical index) |
9 |
| 42 39 not (40 or 41) | 674 |
| 43 limit 42 to (guideline or meta analysis or practice guideline or “review”) |
30 |
| 44 42 not | 43644 |
| 45 limit 44 to yr=1990-2007 | 615 |
| 46 remove duplicates from 45 | 273 |
Discharge Plan data extraction/summary tables
| Study Year | ||||
| UI number | ||||
| Methods Study design description |
||||
| Randomization method | ||||
| Allocation concealment | ||||
| Blinding | ||||
| Number of centers | ||||
| Recruitment years | ||||
| Duration of followup | ||||
| Participants Country |
||||
| Study inclusion criteria | ||||
| Study exclusion criteria | ||||
| Overall | Intervention | Controls | ||
|---|---|---|---|---|
| N randomized | ||||
| Mean age (SD) y | ||||
| Males % | ||||
| Race / Ethnicity % | ||||
| Severity of heart failure (at index admission) | NYHA: LVEF%: |
NYHA: LVEF%: |
||
| Severity of heart failure (at baseline) | NYHA: LVEF%: |
NYHA: LVEF%: |
||
| Duration of CHF | ||||
| History - Myocardial infarction | ||||
| History of other CVD disease | ||||
| ACE inhibitor use | ||||
| B-blockers | ||||
| Diuretics | ||||
| Other medications | ||||
| Interventions | ||||
| Duration of intervention | ||||
| Intervention group name | ||||
| Description of intervention During index hospitalization |
||||
| After discharge | ||||
| Description of comparator | ||||
| Followup times | ||||
| Statistical Analyses | ||||
| Intention to treat | ||||
| Adjusted analyses | ||||
| Outcomes description | ||||
| Primary endpoint (with definition) | ||||
| Secondary endpoint (with definition) | ||||
| Notes | ||||
| Rationale for sample size | ||||
| Reasons for exclusion | ||||
| List biases | ||||
| Funding source | ||||
| Is there any difference between groups at baseline | ||||
Discharge Plan data extraction/summary tables
| APPLICABILITY | QUALITY | ||
|---|---|---|---|
| Wide Applicability:sample representative of Medicare population in relevant setting. Patient’s age (older adult), gender, spectrum of disease severity and type, etc are representative of population of interest. |
A Good quality:Prospective, no obvious biases or reporting errors, <20% dropout, complete reporting of data. |
||
| Moderate Applicability:sample is an important sub-group of population of interest. Possibly limited to a narrow or young age range, type of disease, gender etc. |
B Fair quality:Problems with study/paper unlikely to cause major bias.. |
||
| Narrow Applicability:sample represents only a narrow, atypical subgroup of population of interest, or old study. |
C Poor quality:Cannot exclude possible significant biases. Poor methods, incomplete data, reporting errors. |
||
| If applicability is graded narrow or moderate, what are the limiting factors? |
If Quality is rated B or C, what are the limiting factors? (i.e., incomplete data, errors in analysis, definitions not clear, poor follow-up, dropouts) |
||
Summary table templates
Randomized Controlled Studies (Intervention vs. Control), For event rates
Population recruited:
| Outcome | Study, Year Country |
Followup Duration (Intervention y) |
No. Analyzed | Control Used |
Severity of CHF |
Intervention components |
Event Rate | Net change |
P within |
P Between |
Quality | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Interv | Control | Interv | Control | ||||||||||
Randomized Controlled Studies (Intervention vs. Control), For continuous measures or that provide odds/risk ratio
Population recruited:
| Outcome | Study, Year Country |
Followup Duration (Intervention y) |
No. Analyzed | Control Used |
Severity of CHF |
Intervention components |
Baseline | Results/Final | Quality | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Interv | Control | Metric/ Units |
Interv | Control | P Between |
||||||||
| Text results: | |||||||||||||
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