Public Health Emergency Preparedness
This resource was part of AHRQ's Public Health Emergency Preparedness (PHEP) program, which was discontinued on June 30, 2011, in a realignment of Federal efforts.
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Chapter 3. Pandemic Flu
This chapter describes the assumptions for the flu scenario, including:
- The severity categories.
- The arrival pattern of casualties at the hospital(s).
- The length of stay by hospital unit (i.e., ED, ICU, and the floor).
- The path probability within the hospital(s) and the length of stay.
- The overall outcome probabilities (i.e., probability of discharge and probability of death).
- The assumed level of resource consumption per patient per day per hospital unit.
The flu scenario incorporates hospital resource utilization and patient outcomes similar to those documented during the 2009 influenza A (H1N1) pandemic.
Footnotes in the text of a particular section refer to references at the end of the section. In the absence of specific references, parameter estimates were obtained from general references listed in the Hospital Module section.
3.1 Severity Categories
For the flu scenario, patients arrive at the hospital(s) in one of two conditions:
- Moderate: After arriving at the Emergency Department (ED), patients will be moved to the floor for medical care.
- Severe: After arriving at the ED, patients will be moved to the intensive care unit (ICU) for medical care.
In the model, persons with mild symptoms are not hospitalized.
Users have the option of specifying either the number and type or simply the number of persons who become infected with flu. A user-specified percentage of these patients will require hospitalization.
If the user specifies only the number of infected persons, the model assumes these persons are randomly selected from among all infected persons. The distribution of infected persons in this case is as follows:
| Casualty Condition |
Percent |
| Moderate: After arriving at the ED, patients will be moved to the floor for medical care |
85% |
| Severe: After arriving at the ED, patients will be moved to the ICU for medical care |
15% |
3.2 Casualty Arrival Pattern
Casualties are assumed to present at the hospital(s) when symptoms appear. For this scenario, we used data from the Models of Infectious Disease Agent Study (MIDAS) group3 to estimate the temporal distribution of arrivals to the hospital. The MIDAS data closely follow a Normal distribution with mean 114 days and standard deviation 22 days.
3.3 Length of Stay (LOS) By Hospital Unit
The assumed average length of stay (in days) of patients the ED, ICU, and the floor is:
| Average LOS by Hospital Unit |
Moderate |
Severe |
| ED |
1 |
1 |
| Floor, not via ICU |
5.3 |
5.3 |
| Floor, via ICU |
5.3 |
5.3 |
| ICU |
8 |
8 |
3.4 Combined Path Probabilities and Lengths of Stay
The table below shows the assumed probabilities of different "paths" through the hospital(s).
| Path |
Moderate |
Severe |
| ED → Discharge |
0% |
0% |
| ED → Death |
0% |
0% |
| ED → Floor → Discharge |
89% |
4% |
| ED → Floor → Death |
5% |
0% |
| ED → Floor → ICU → Death |
1% |
0% |
| ED → Floor → ICU → Floor → Discharge |
4% |
1% |
| ED → Floor → ICU → Floor → Death |
0% |
0% |
| ED → ICU → Death |
0% |
21% |
| ED → ICU → Floor → Discharge |
1% |
71% |
| ED → ICU → Floor → Death |
0% |
4% |
The breakdown of length of stay by patient type summed over all paths is:
| Average LOS by Patient Outcome |
Moderate |
Severe |
| Survivors |
6.5 |
13.6 |
| Fatalities |
5.1 |
6.4 |
| Average Combined |
6.4 |
11.8 |
3.5 Overall Outcome Probabilities
Based on these inputs, the overall discharge and death probabilities are:
| Outcome |
Moderate |
Severe |
| Discharge |
94% |
75% |
| Death |
6% |
25% |
3.6 Resources Consumed Per Patient Per Day
The assumed level of resource consumption per patient per day is shown in the table below:
| Resource |
Units |
Category |
Subcategory |
Lambdaa |
Moderate |
Severe |
| ED |
ICU |
Floor |
ED |
ICU |
Floor |
| Adult med/surg bed |
EA (Each) |
Capacity |
Adult Med/Surg |
1 |
0.167 |
0.000 |
0.667 |
0.167 |
0.000 |
0.667 |
| Adult ICU bed |
EA (Each) |
Capacity |
Adult ICU |
1 |
0.000 |
0.667 |
0.000 |
0.000 |
0.667 |
0.000 |
| Pediatric med/surg bed |
EA (Each) |
Capacity |
Pediatric Med/Surg |
1 |
0.083 |
0.000 |
0.333 |
0.083 |
0.000 |
0.333 |
| Pediatric ICU bed |
EA (Each) |
Capacity |
Pediatric ICU |
1 |
0.000 |
0.333 |
0.000 |
0.000 |
0.333 |
0.000 |
| Burn bed |
EA (Each) |
Capacity |
Burn |
1 |
0.000 |
0.000 |
0.000 |
0.000 |
0.000 |
0.000 |
| Operating room |
EA (Each) |
Capacity |
OR |
0 |
0.000 |
0.000 |
0.000 |
0.000 |
0.000 |
0.000 |
| Airborne isolation room |
EA (Each) |
Capacity |
Isolation |
0.7 |
0.000 |
0.000 |
0.000 |
0.000 |
0.000 |
0.000 |
| Intensivists (CCM) |
FTE |
Staff |
CCM |
0.9 |
0.021 |
0.042 |
0.000 |
0.042 |
0.042 |
0.000 |
| Critical care nurses (CCN) |
FTE |
Staff |
CCN |
1 |
0.000 |
0.333 |
0.000 |
0.125 |
0.333 |
0.000 |
| Surgeons |
FTE |
Staff |
Surgeon |
0 |
0.000 |
0.004 |
0.000 |
0.000 |
0.004 |
0.000 |
| Non-intensivists (MD) |
FTE |
Staff |
MD |
1 |
0.042 |
0.000 |
0.021 |
0.042 |
0.000 |
0.021 |
| Non-critical care nurses (RN/LPN) |
FTE |
Staff |
RN |
1 |
0.083 |
0.000 |
0.125 |
0.042 |
0.000 |
0.125 |
| Pharmacists (PharmD/RPh) |
FTE |
Staff |
Pharmacist |
0.7 |
0.000 |
0.021 |
0.000 |
0.021 |
0.021 |
0.000 |
| Respiratory Therapists (RT) |
FTE |
Staff |
RT |
1 |
0.000 |
0.042 |
0.000 |
0.021 |
0.042 |
0.000 |
| Mortuary |
FTE |
Staff |
Mortuary |
0 |
0.000 |
0.029 |
0.000 |
0.000 |
0.029 |
0.000 |
| Adult mechanical ventilator |
EA (Each) |
Capacity |
Ventilator |
0.92 |
0.000 |
0.480 |
0.000 |
0.080 |
0.480 |
0.000 |
| Pediatric mechanical ventilator |
EA (Each) |
Capacity |
Ventilator |
0.92 |
0.000 |
0.240 |
0.000 |
0.040 |
0.240 |
0.000 |
| Adult ventilator circuit |
EA (Each) |
Equipment |
Ventilator Kit |
0.92 |
0.000 |
0.312 |
0.000 |
0.416 |
0.312 |
0.000 |
| Pediatric ventilator circuit |
EA (Each) |
Equipment |
Ventilator Kit |
0.92 |
0.000 |
0.156 |
0.000 |
0.208 |
0.156 |
0.000 |
| Closed circuit suction catheter 14F |
EA (Each) |
Equipment |
Ventilator Kit |
0.92 |
0.000 |
0.312 |
0.000 |
0.416 |
0.312 |
0.000 |
| Closed circuit suction catheter 8-12F |
EA (Each) |
Equipment |
Ventilator Kit |
0.92 |
0.000 |
0.156 |
0.000 |
0.208 |
0.156 |
0.000 |
| Humidification and Filtration Unit (HMEF) |
EA (Each) |
Equipment |
Ventilator Kit |
0.92 |
0.000 |
0.328 |
0.000 |
0.437 |
0.328 |
0.000 |
| Endotracheal tube, 6.5-8mm ID |
EA (Each) |
Equipment |
Intubation |
0.92 |
0.000 |
0.206 |
0.000 |
0.416 |
0.206 |
0.000 |
| Endotracheal tube, 3-6mm ID |
EA (Each) |
Equipment |
Intubation |
0.92 |
0.000 |
0.103 |
0.000 |
0.208 |
0.103 |
0.000 |
| Laryngoscope blades, adult |
EA (Each) |
Equipment |
Intubation |
0.92 |
0.000 |
0.125 |
0.000 |
0.416 |
0.125 |
0.000 |
| Laryngoscope blades, pediatric |
EA (Each) |
Equipment |
Intubation |
0.92 |
0.000 |
0.062 |
0.000 |
0.208 |
0.062 |
0.000 |
| Laryngoscope handles |
EA (Each) |
Equipment |
Intubation |
0.92 |
0.000 |
0.187 |
0.000 |
0.624 |
0.187 |
0.000 |
| Endotracheal stylette |
EA (Each) |
Equipment |
Intubation |
0.92 |
0.000 |
0.187 |
0.000 |
0.624 |
0.187 |
0.000 |
| Resuscitation bag, adult |
EA (Each) |
Equipment |
Ventilator Kit |
0.92 |
0.000 |
0.125 |
0.000 |
0.416 |
0.125 |
0.000 |
| Resuscitation bag, pediatric |
EA (Each) |
Equipment |
Ventilator Kit |
0.92 |
0.000 |
0.062 |
0.000 |
0.208 |
0.062 |
0.000 |
| Ventilator Oxygen (O2) |
Liters Liquid O2 |
Supplies |
Oxygen |
0.92 |
0.000 |
4.535 |
0.000 |
1.134 |
4.535 |
0.000 |
| NC Oxygen (O2) |
Liters Liquid O2 |
Supplies |
Oxygen |
0.92 |
1.675 |
1.876 |
6.700 |
0.000 |
1.876 |
6.700 |
| Pulse oximeter |
EA (Each) |
Equipment |
O2 Monitoring |
0.92 |
0.007 |
1.000 |
0.007 |
0.250 |
1.000 |
0.007 |
| Finger pulse oximeter strip |
EA (Each) |
Equipment |
O2 Monitoring |
0.92 |
1.000 |
0.650 |
0.650 |
1.000 |
0.650 |
0.650 |
| End tidal CO2 detector, adult |
EA (Each) |
Equipment |
O2 Monitoring |
0 |
0.000 |
0.624 |
0.000 |
0.416 |
0.208 |
0.000 |
| End tidal CO2 detector, pediatric |
EA (Each) |
Equipment |
O2 Monitoring |
0 |
0.000 |
0.312 |
0.000 |
0.208 |
0.010 |
0.000 |
| Oxygen tubing (high flow) |
EA (Each) |
Equipment |
O2 Monitoring |
0.92 |
0.000 |
0.182 |
0.000 |
0.673 |
0.120 |
0.000 |
| Oxygen tubing (low flow) |
EA (Each) |
Equipment |
O2 Monitoring |
0.92 |
0.325 |
0.000 |
0.650 |
0.000 |
0.000 |
0.650 |
| Nebulizer sets |
EA (Each) |
Equipment |
O2 Monitoring |
0.92 |
1.300 |
0.650 |
0.429 |
1.300 |
0.650 |
0.429 |
| Nasal cannulas |
EA (Each) |
Equipment |
O2 Monitoring |
0.92 |
1.300 |
0.182 |
0.429 |
0.000 |
0.000 |
0.429 |
| Oxygen mask, adult |
EA (Each) |
Equipment |
O2 Monitoring |
0.92 |
0.000 |
0.286 |
0.000 |
0.867 |
0.286 |
0.000 |
| Oxygen mask, pediatric |
EA (Each) |
Equipment |
O2 Monitoring |
0.92 |
0.000 |
0.143 |
0.000 |
0.433 |
0.143 |
0.000 |
| Standard radiograph |
EA (Each) |
Radiology |
CXR |
0.5 |
0.021 |
0.021 |
0.000 |
0.021 |
0.021 |
0.000 |
| Computed tomography |
Machine Time (24h) |
Radiology |
CT |
0 |
0.000 |
0.000 |
0.000 |
0.021 |
0.000 |
0.000 |
| FAST |
Machine Time (24h) |
Radiology |
FAST |
0 |
0.000 |
0.000 |
0.000 |
0.000 |
0.000 |
0.000 |
| Radiology supplies single study |
EA (Each) |
Supplies |
Rad Supplies |
0.9 |
1.300 |
1.300 |
0.000 |
2.600 |
1.300 |
0.000 |
| Chemistry lab machine |
Machine Time (24h) |
Laboratory |
Chem |
0.9 |
0.021 |
0.021 |
0.010 |
0.042 |
0.021 |
0.010 |
| Chemistry lab supplies advanced panel |
EA (Each) |
Supplies |
Chem Supplies |
0.9 |
1.300 |
1.300 |
0.650 |
2.600 |
1.300 |
0.650 |
| Hematology lab machines |
Machine Time (24h) |
Laboratory |
Heme |
0.9 |
0.021 |
0.021 |
0.010 |
0.042 |
0.021 |
0.010 |
| Hematology lab supplies advanced panel |
EA (Each) |
Supplies |
Heme Supplies |
0.9 |
1.300 |
1.300 |
0.650 |
2.600 |
1.300 |
0.650 |
| Micro/Virology lab machines |
Machine Time (24h) |
Laboratory |
Micro |
0.9 |
0.021 |
0.021 |
0.000 |
0.042 |
0.021 |
0.000 |
| Micro lab supplies advanced diagnostic |
EA (Each) |
Supplies |
Micro Supplies |
0 |
1.300 |
1.300 |
0.000 |
2.600 |
1.300 |
0.000 |
| Chest tube drainage system |
EA (Each) |
Supplies |
Chest Tube |
0.8 |
0.000 |
0.034 |
0.000 |
0.169 |
0.034 |
0.000 |
| NG tubes sizes 6F-16F |
EA (Each) |
Supplies |
NG Tube |
0.8 |
0.000 |
0.486 |
0.000 |
0.649 |
0.486 |
0.000 |
| Enteral feeding tube |
EA (Each) |
Supplies |
Feeding Tube |
1 |
0.000 |
0.468 |
0.000 |
0.000 |
0.468 |
0.000 |
| Temperature monitor, adult |
Machine Time (24h) |
Supplies |
TempA |
0.9 |
0.005 |
0.028 |
0.009 |
0.005 |
0.028 |
0.009 |
| Temperature monitor, pediatric |
Machine Time (24h) |
Supplies |
TempP |
0.9 |
0.002 |
0.014 |
0.005 |
0.002 |
0.014 |
0.005 |
| Temperature monitor cover |
EA (Each) |
Supplies |
TempCov |
1 |
2.600 |
7.800 |
5.200 |
2.600 |
7.800 |
5.200 |
| Urine output, Foley catheter 8F-12F |
EA (Each) |
Supplies |
Foley |
1 |
0.000 |
0.156 |
0.000 |
0.624 |
0.156 |
0.000 |
| Urine output, monitor bag |
EA (Each) |
Supplies |
Urinary Bag |
0 |
0.000 |
0.390 |
0.000 |
0.624 |
0.390 |
0.000 |
| BP cuffs, adult |
Machine Time (24h) |
Equipment |
BPCuffA |
0.9 |
0.014 |
0.056 |
0.014 |
0.014 |
0.056 |
0.014 |
| BP cuffs, pediatric |
Machine Time (24h) |
Equipment |
BPCuffP |
0.9 |
0.007 |
0.028 |
0.007 |
0.007 |
0.028 |
0.007 |
| N95/surgical masks |
EA (Each) |
Supplies |
Mask |
1 |
0.390 |
2.600 |
2.600 |
3.900 |
2.600 |
2.600 |
| Face shields |
EA (Each) |
Supplies |
Shield |
1 |
0.800 |
0.800 |
0.100 |
0.800 |
0.800 |
0.100 |
| Latex, non-sterile gloves |
EA (Each) |
Supplies |
Glove, latex |
1 |
3.250 |
3.250 |
3.250 |
3.250 |
3.250 |
3.250 |
| Latex-free, non-sterile gloves |
EA (Each) |
Supplies |
Glove, latex-free |
1 |
3.250 |
3.250 |
3.250 |
3.250 |
3.250 |
3.250 |
| Latex-free, sterile gloves |
EA (Each) |
Supplies |
Glove, sterile |
0.8 |
2.600 |
2.600 |
0.000 |
2.600 |
2.600 |
0.000 |
| Gown, standard |
EA (Each) |
Supplies |
Gown |
1 |
1.300 |
1.300 |
0.000 |
1.300 |
1.300 |
0.000 |
| Gown, fluid resistant |
EA (Each) |
Supplies |
GownFluidR |
0.7 |
0.975 |
0.975 |
0.000 |
0.975 | 0.975 |
0.000 |
| Alcohol hand sanitizer (L) |
Liters |
Supplies |
Sanitizer |
1 |
0.100 |
0.100 | 0.100 | 0.100 | 0.100 | 0.100 |
| Bleach-based cleaner (L) |
Liters |
Supplies |
Sanitizer |
1 |
0.100 |
0.100 |
0.100 |
0.100 |
0.100 |
0.100 |
| Hazmat red bag liner |
EA (Each) |
Supplies |
Bag |
1 |
1.000 |
2.000 |
0.250 |
1.000 |
2.000 |
0.250 |
| Intravenous (IV) catheters, 18g with protectocath guard |
EA (Each) |
IV |
IVs |
0.92 |
0.390 |
0.130 |
0.130 |
0.390 |
0.130 |
0.130 |
| IV catheters, 20g with protectocath guard |
EA (Each) |
IV |
IVs |
0.92 |
0.390 |
0.130 |
0.130 |
0.390 |
0.130 |
0.130 |
| IV catheters, 22g with protectocath guard |
EA (Each) |
IV |
IVs |
0.92 |
0.260 |
0.087 |
0.087 |
0.260 |
0.087 |
0.087 |
| IV catheters, 24g with protectocath guard |
EA (Each) |
IV |
IVs |
0.92 |
0.260 |
0.087 |
0.087 |
0.260 |
0.087 |
0.087 |
| IV start kits |
EA (Each) |
IV |
IVs |
0.92 |
1.300 |
0.433 |
0.433 |
1.300 |
0.433 |
0.433 |
| IV tubing w/Buretrol drip set for peds |
EA (Each) |
IV |
IV Admin Set |
0.92 |
0.433 |
0.144 |
0.144 |
0.433 |
0.144 |
0.144 |
| IV tubing w/standard macrodrip for adults |
EA (Each) |
IV |
IV Admin Set |
0.92 |
0.867 |
0.289 |
0.289 |
0.867 |
0.289 |
0.289 |
| Sodium chloride flush 0.9% 3ml |
EA (Each) |
IV |
IV Flush |
0.92 |
2.600 |
7.800 |
7.800 |
2.600 |
7.800 |
7.800 |
| Povidone iodine 10% swab sticks triples |
EA (Each) |
IV |
IV site prep |
0.92 |
1.300 |
0.433 |
0.433 |
1.300 |
0.433 |
0.433 |
| IV site transparent dressing |
EA (Each) |
IV |
IV dressing |
0.92 |
1.300 |
0.433 |
0.433 |
1.300 |
0.433 |
0.433 |
| Gauze pad 4x4 |
EA (Each) |
IV |
IV dressing |
0.92 |
5.200 |
5.200 |
5.200 |
5.200 |
5.200 |
5.200 |
| Heparin lock flush kit, 100 units ml |
EA (Each) |
IV |
Heplock Kit |
1 |
2.600 |
7.800 |
7.800 |
2.600 |
7.800 |
7.800 |
| Syringes, 10cc |
EA (Each) |
IV |
IV Admin Set |
0.92 |
1.430 |
1.430 |
1.430 |
1.430 |
1.430 |
1.430 |
| Syringes, 3cc |
EA (Each) |
IV |
IV Admin Set |
0.92 |
5.200 |
5.200 |
5.200 |
5.200 |
5.200 |
5.200 |
| Needles, butterfly, 23g |
EA (Each) |
IV |
IVs |
0.92 |
0.043 |
0.043 |
0.043 |
0.043 |
0.043 |
0.043 |
| Needles, butterfly, 25g |
EA (Each) |
IV |
IVs |
0.92 |
0.043 |
0.043 |
0.043 |
0.043 |
0.043 |
0.043 |
| Needles, sterile 18g |
EA (Each) |
IV |
IVs |
0.92 |
2.600 |
2.600 |
2.600 |
2.600 |
2.600 |
2.600 |
| Needles, sterile 21g |
EA (Each) |
IV |
IVs |
0.92 |
2.600 |
2.600 |
2.600 |
2.600 |
2.600 |
2.600 |
| Needles, sterile 25g |
EA (Each) |
IV |
IVs |
0.92 |
0.043 |
0.043 |
0.043 |
0.043 |
0.043 |
0.043 |
| Catheter interosseous |
EA (Each) |
IV |
IO |
0 |
0.043 |
0.022 |
0.000 |
0.043 |
0.022 |
0.000 |
| Sodium chloride 0.9% solution IV, 1000 ml |
EA (Each) |
IVF |
NAe |
0.92 |
0.553 |
2.211 |
1.690 |
0.553 |
2.211 |
1.690 |
| Dextrose 5% sodium chloride 0.45% inj. 1000 ml |
EA (Each) |
IVF |
D51/2NS |
0.92 |
0.368 |
1.474 |
1.127 |
0.368 |
1.474 |
1.127 |
| D5W or sterile water piggybacks of 50-250ml size |
EA (Each) |
IVF |
D5W |
1 |
2.600 |
2.600 |
1.300 |
2.600 |
2.600 |
1.300 |
| Saline for injection, sterile 10 ml |
EA (Each) |
IVF |
Saline |
1 |
2.600 |
2.600 |
1.300 |
2.600 |
2.600 |
1.300 |
| IV pole |
EA (Each) |
IVF |
IV set |
1 |
1.300 | 1.300 |
1.300 |
1.300 | 1.300 |
1.300 |
| Matched RBC |
Units |
Blood Product |
RBC |
0 |
0.000 |
0.100 |
0.000 |
0.000 |
0.100 |
0.000 |
| Platelets |
Pack |
Blood Product |
PLT |
0 |
0.000 |
0.100 |
0.000 |
0.000 |
0.100 |
0.000 |
| FFP |
Units |
Blood Product |
FFP |
0.6 |
0.000 |
0.250 |
0.000 |
0.000 |
0.250 |
0.000 |
| Alcohol pads |
EA (Each) |
Supplies |
Alcohol |
0.92 |
1.950 |
7.800 |
3.900 |
7.800 |
7.800 |
3.900 |
| Band-aids |
EA (Each) |
Supplies |
BandAid |
0.92 |
0.325 |
1.300 |
1.300 |
1.300 |
1.300 |
1.300 |
| Basins, bath |
EA (Each) |
Supplies |
Basin |
0.92 |
1.300 |
1.300 |
1.300 |
1.300 |
1.300 |
1.300 |
| Bathing supply, prepackaged |
EA (Each) |
Supplies |
Bathing |
0.92 |
1.300 |
1.300 |
1.300 |
1.300 |
1.300 |
1.300 |
| Bedpans, regular |
EA (Each) |
Supplies |
Bedpan |
0.92 |
1.300 |
1.300 |
1.300 |
1.300 |
1.300 |
1.300 |
| Blankets |
EA (Each) |
Supplies |
Blanket |
0.92 |
2.600 |
2.600 |
2.600 |
2.600 |
2.600 |
2.600 |
| Diapers, adult |
EA (Each) |
Supplies |
DiaperA |
0.92 |
0.043 |
0.173 |
0.173 |
0.043 |
0.173 |
0.173 |
| Diapers, infant |
EA (Each) |
Supplies |
DiaperI |
0.92 |
0.087 |
0.346 |
0.346 |
0.087 |
0.346 |
0.346 |
| Diapers, pediatric |
EA (Each) |
Supplies |
DiaperP |
0.92 |
0.081 |
0.325 |
0.325 |
0.081 |
0.325 |
0.325 |
| Bed linen |
EA (Each) |
Supplies |
Linen |
1 |
1.300 | 1.300 |
1.300 |
1.300 | 1.300 |
1.300 |
| Patient gown |
EA (Each) |
Supplies |
PTGown |
1 |
1.300 | 1.300 |
1.300 |
1.300 | 1.300 |
1.300 |
| Oseltamivir 75mg po dose |
EA (Each) |
Pharmaceutical |
Antiviral |
0.7 |
1.000 |
2.000 | 2.000 |
0.500 |
1.000 | 1.000 |
| Zanamivir 10mg po dose |
EA (Each) |
Pharmaceutical |
Antiviral |
0.7 |
0.000 |
0.000 |
0.000 |
0.500 |
1.000 | 1.000 |
| Rimantidine 100mg po dose |
EA (Each) |
Pharmaceutical |
Antiviral |
0.7 |
0.000 |
0.000 |
0.000 |
0.500 |
1.000 | 1.000 |
| Ceftriaxone 1g IV dose |
EA (Each) |
Pharmaceutical |
IV Beta Lactam |
0.92 |
0.270 |
0.540 |
0.540 |
0.270 |
0.540 |
0.540 |
| Levofloxacin 750mg IV dose |
EA (Each) |
Pharmaceutical |
IV Quinolone |
0.92 |
0.310 |
0.610 |
0.610 |
0.310 |
0.610 |
0.610 |
| Nafcillin sodium 1g IV dose |
EA (Each) |
Pharmaceutical |
IV Nafcillin |
0.92 |
0.160 |
0.640 |
0.640 |
0.160 |
0.640 |
0.640 |
| Vancomycin 1g IV dose |
EA (Each) |
Pharmaceutical |
IV Vanco |
0.92 |
0.834 |
0.834 |
0.834 |
0.834 |
0.834 |
0.834 |
| Succinylcholine chloride (mg) |
mg |
Pharmaceutical |
Intubation |
0 |
0.000 |
33.341 |
0.000 |
22.227 |
11.114 |
0.000 |
| Rocuronium (mg) |
mg |
Pharmaceutical |
Intubation |
0 |
0.000 |
23.026 |
0.000 |
15.351 |
7.675 |
0.000 |
| Fentanyl citrate (mcg) |
mcg |
Pharmaceutical |
Intubation |
0 |
0.000 |
46.053 |
0.000 |
30.702 |
15.351 |
0.000 |
| Propofol (mg) |
mg |
Pharmaceutical |
Intubation |
0 |
0.000 |
52.296 |
0.000 |
34.864 |
17.432 |
0.000 |
| Midazolam (mg) |
mg |
Pharmaceutical |
Intubation |
0 |
0.000 |
1.104 |
0.000 |
0.736 |
0.368 |
0.000 |
| LMW heparin, inj. |
EA (Each) |
Pharmaceutical |
ProphylaxisDVT |
1 |
0.000 |
2.000 |
2.000 |
0.000 |
2.000 |
2.000 |
| Aerosol spacer, pediatric |
EA (Each) |
Pharmaceutical |
Bronchodilator |
0 |
0.433 |
0.433 |
0.433 |
0.433 |
0.433 |
0.433 |
| Albuterol (mg) |
EA (Each) |
Pharmaceutical |
Bronchodilator |
0 |
0.148 |
5.938 |
0.594 |
0.990 |
5.938 |
3.960 |
| Ipratropium bromide, inh. (mg) |
EA (Each) |
Pharmaceutical |
Bronchodilator |
0.9 |
0.021 |
0.828 |
0.083 |
0.138 |
0.828 |
0.552 |
| Antipyretic pediatric (dose) |
EA (Each) |
Pharmaceutical |
Antipyretic |
0 |
0.333 |
1.332 |
1.332 |
0.333 |
1.332 |
1.332 |
| Antipyretic adult (tab) |
EA (Each) |
Pharmaceutical |
Antipyretic |
0 |
0.667 |
2.668 |
2.668 |
0.667 |
2.668 |
2.668 |
| GI acid blocker |
EA (Each) |
Pharmaceutical |
ProphylaxisGI |
0.9 |
0.000 |
2.000 |
2.000 |
0.000 |
2.000 |
2.000 |
| Methylprednisolone (mg) |
EA (Each) |
Pharmaceutical |
Steroid |
0.9 |
0.000 |
18.000 |
0.000 |
0.000 |
18.000 |
0.000 |
a. Lambda captures the resource requirement decay rate for a resource. Lambda = 1 implies no decay; the patient requires a constant amount of the resource while s/he is hospitalized. Lambda <1 implies that less of the resource is required each day the patient is hospitalized. Go to section 2.2 for details.
3.7 References
1.
Germann TC, Kadau K, Longini IM Jr, Macken CA. Mitigation strategies for pandemic influenza in the United States. Proc Natl Acad Sci U S A 2006;103(15):5935-5940.
2.
Healthcare Cost and Utilization Project. Rockville, MD: Agency for Healthcare Research and Quality; 2010. Available at http://hcupnet.ahrq.gov. Accessed July 27, 2010.
3. Longini IM Jr, Halloran ME, Nizam A, Yang Y. Containing pandemic influenza with antiviral agents. Am J Epidemiol 2004;159(7):623-33.
4.
National Heart, Lung, and Blood Institute Acute Respiratory Distress Syndrome (ARDS) Clinical Trials Network, Wiedemann HP, Wheeler AP, et al. Comparison of two fluid-management strategies in acute lung injury. N Engl J Med 2006;354(24):2564-75.
5.
Office of Emergency Medical Services. Emergency Medical Services Pre-Hospital Treatment Protocols. Official Version 6.04. Boston: Massachusetts Department of Public Health; 2006.
6.
Rubinson L, Nuzzo JB, Talmor DS, O'Toole T, Kramer BR, Inglesby TV. Augmentation of hospital critical care capacity after bioterrorist attacks or epidemics: recommendations of the Working Group on Emergency Mass Critical Care. Crit Care Med 2005;33(10):2393-403.
3. The Models of Infectious Disease Agent Study (MIDAS) is a collaboration of research and informatics groups to develop computational models of the interactions between infectious agents and their hosts, disease spread, prediction systems, and response strategies. For more information, go to: http://www.nigms.nih.gov/Initiatives/MIDAS/
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