Improving Office Care for Chest Pain (Text Version)
On September 19, 2011, Thomas Sequist made this presentation at the 2011 Annual Conference. Select to access the PowerPoint® presentation (660 KB). Plugin Software Help.
Slide 1
Improving Office Care for Chest Pain
Thomas D. Sequist, MD MPH
Associate Professor of Medicine and Health Care Policy
Brigham and Woman's Hospital, Division of General Medicine
Harvard Medical School, Department of Health Care Policy
Harvard Vanguard Medical Associates
Slide 2
Why Chest Pain?
- Chest pain is a common symptom:
- Increasing burden in primary care.
- Frequent missed diagnosis of acute myocardial infarction (MI).
- Excess utilization of resources.
Slide 3
Patient Care Model
Image: A flowchart of the Patient Care Model is shown:
- Primary care visit:
- Home without further testing.
- Home with further testing.
- Emergency Department:
- Discharged.
- Chest Pain Unit.
- Inpatient.
- Intensive Care Unit (ICU).
Slide 4
Patient Care Model
Image: A flowchart of the Patient Care Model is shown:
- Primary care visit:
- Home without further testing.
- Home with further testing.
- Emergency Department:
- Discharged.
- Chest Pain Unit.
- Inpatient.
- ICU.
Dotted lines now connect "Home without further testing" and "Home with further testing" to the items under "Emergency Department."
Slide 5
Primary Care Challenges
- Low risk population:
- Limit excess resource utilization.
- Avoid missed diagnoses.
- Time-limited care:
- Cannot usually observe over several hours.
- No immediate cardiac stress testing.
- No immediate cardiac enzymes.
Slide 6
Can the Framingham Score Help?
- Main utility is to raise awareness.
- Framingham risk score (FRS) variables are generally available.
- FRS compares favorably with exercise stress testing.
Slide 7
Defining High Risk Patients
| FRS Cutoff | Sensitivity | Specificity |
|---|---|---|
| ≥5% | 96 | 61 |
| ≥10% | 85 | 75 |
| ≥20% | 54 | 86 |
Slide 8
Study Questions
- Can risk score alerts within an electronic health record (EHR) improve risk-appropriate care for patients with chest pain?
- What are the additional opportunities to improve the efficiency of chest pain care?
Slide 9
Harvard Vanguard Medical Associates
- Multi-specialty group practice.
- Integrated electronic health record.
- 15 ambulatory health centers.
- 175 primary care physicians.
- 300,000 adult patients.
Image: A map of eastern Massachusetts shows the locations of Harvard Vanguard Medical Associates offices.
Slide 10
Randomization Scheme
Image: A flowchart of the Randomization Scheme is shown:
292 Primary Care Clinicians
7,083 patients (≥30 years old)
- Intervention Group: 149 clinicians, 3,634 patients:
- High Risk, 717 patients.
- Low Risk, 2917 patients.
- Control Group: 143 clinicians, 3,449 patients:
- High Risk, 610 patients.
- Low Risk, 2839 patients.
Slide 11
Intervention Design
- Identification of patients with chest pain:
- Medical assistant training.
- Automated calculation of Framingham Risk Score.
- Delivery of risk-appropriate recommendations via electronic alerts.
Slide 12
Risk Appropriate Recommendations
- High risk patients (FRS = 10%):
- Electrocardiogram performance.
- Aspirin therapy.
- Low risk patients (FRS <10%):
- Avoidance of cardiac stress testing.
Slide 13
Entry of Chest Pain Complaint
Image: A screenshot shows "Chest Pain" being selected as Chief Complaint.
Slide 14
High Risk Patient Alert
Image: A screenshot shows a sample High Risk Patient Alert.
Slide 15
Low Risk Patient Alert
Image: A screenshot shows a sample Low Risk Patient Alert.
Slide 16
SmartLink (.frsdetail)
Image: A screenshot of SmartLink is shown with patient details entered under "Notes."
Slide 17
Baseline Patient Characteristics
| Characteristics | Intervention (n = 3,634) | Control (n = 3,449) | p value | |
|---|---|---|---|---|
| Mean age, years | 49.7 | 48.6 | 0.001 | |
| Female, % | 63 | 65 | 0.03 | |
| Insurance | Commercial | 76 | 77 | 0.01 |
| Medicare | 14 | 11 | ||
| Medicaid | 8 | 9 | ||
| Uninsured | 3 | 3 | ||
| Framingham Risk Score | <10% | 80 | 82 | 0.03 |
| ≥10% | 20 | 18 | ||
Slide 18
Clinical Care and Outcomes
| High Risk (n=1327) | Low Risk (n=5756) | p value | ||
|---|---|---|---|---|
| Evaluation and treatment | Electrocardiogram | 50 | 43 | <0.001 |
| Aspirin therapy | 19 | 7 | <0.001 | |
| Cardiac stress test | 17 | 10 | <0.001 | |
| Follow up care | Home | 91 | 96 | <0.001 |
| Hospitalized | 7 | 3 | <0.001 | |
| Diagnoses | Acute myocardial infarction* | 1.1 | 0.2 | 0.01 |
* Among 26 cases of AMI, 10 (36%) represented missed diagnoses.
Slide 19
Impact of Electronic Alerts
Image: Bar chart shows the following data:
| High Risk Patients | Low Risk Patients | ||
|---|---|---|---|
| EKG Performance | Aspirin Therapy | Cardiac Stress Testing | |
| Intervention | 51 | 20 | 10 |
| Control | 48 | 18 | 9 |
Slide 20
Clinician Views on Intervention
Is the Framingham Risk Score a valid tool for evaluating chest pain?
Image: Bar chart shows the following data:
| Always | Often | Sometimes | Rarely or Never | |
|---|---|---|---|---|
| Intervention | 5 | 40 | 47 | 8 |
Slide 21
Clinician Views on Intervention
Is a Risk Score Cutoff of 10% to identify high risk patients...
Image: Bar graph shows the following data:
| Too high | About right | Too low | |
|---|---|---|---|
| Intervention | 12 | 81 | 7 |
Slide 22
Conclusions
- Acute MI is uncommon among primary care patients with chest pain.
- Missed diagnosis of acute MI is common, while many low risk patients undergo cardiac stress testing.
- Electronic risk alerts do not change care patterns.
Slide 23
Implications
- Failure to change care patterns:
- Is it lack of belief in the risk assessment tool?
- Is it failure to deliver information effectively?
- Do we need more comprehensive efforts?
- Electronic health records represent one piece of a multi-component program.
Slide 24
Improving Efficiency of Chest Pain Care
- Map flow of patients from primary care.
- Evaluate cost implications for varied evaluation and management strategies.
- Analyze variation in care patterns.
Slide 25
Patient Care Model
Image: A flowchart of the Patient Care Model is shown:
- Primary care visit:
- Home without further testing.
- Home with further testing.
- Emergency Department:
- Discharged.
- Chest Pain Unit.
- Inpatient.
- ICU.
Slide 26
Estimated Average Costs Per Patient
Image: A flowchart of the Patient Care Model is shown with the data added:
- Primary care visit:
- Home without further testing (55%, $293).
- Home with further testing (40%, $442).
- Emergency Department (5%):
- Discharged (37%, $1,087).
- Chest Pain Unit (47%, $3,192).
- Inpatient (13%, $17,562).
- ICU (3%, $47,575).
Slide 27
Estimated Average Costs Per Patient
Image: A flowchart of the Patient Care Model is shown with the data added. The bolded sections are highlighted in yellow:
- Primary care visit:
- Home without further testing (55%, $293).
- Home with further testing (40%, $442).
- Emergency Department (5%):
- Discharged (37%, $1,087).
- Chest Pain Unit (47%, $3,192).
- Inpatient (13%, $17,562).
- ICU (3%, $47,575).
Slide 28
Physician Level Clinical Variation
Image: A bar graph shows the following data for percentage of patients referred for care within physician practices:
Cardiac Stress Testing*:
- 95% Lower CI: 3.8%.
- Average: 10.8%.
- 95% Upper CI: 26.7%.
Emergency Department Triage*
- 95% Lower CI: 1.3%.
- Average: 4.7%.
- 95% Upper CI: 14.9%.
* p<0.01 for random effects of physician level variation.
Slide 29
How Can the EHR Improve Efficiency?
- Increasing awareness of pre-test probability:
- All variation is within low risk patients.
- Focus on low value emergency department referrals.
- Peer to peer education.
Slide 30
Clinical Process Flow
Image: A flowchart of the Patient Care Model is shown:
- Primary care visit → (Triage) →
- EKG.
- ETT.
- Stress ECHO.
- Stress Nuclear.
- Cardiology.
- Emergency Department → (Triage) →
- Home.
- Chest Pain Unit.
- Inpatient.
- ICU.
- Home.


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