Dual Eligibles with Mental Disorders and Medicare Part D (Text Version)
On September 16, 2009, Sam Zuvekas made this presentation at the 2009 Annual Conference. Select to access the PowerPoint® presentation (851 KB).
Slide 1

Dual Eligibles with Mental Disorders and Medicare Part D: How are They Faring?
Julie Donohue
University of Pittsburgh
Haiden Huskamp
Harvard Medical School
Sam Zuvekas
Agency for Healthcare Research and Quality
Slide 2

Context
- 6 million Medicare beneficiaries dually eligible for Medicaid moved to Medicare Part D drug plans.
- Random assignment to one of multiple benchmark plans, can switch
- Estimated 60% of disabled and 20% of elderly dual-eligibles have mental disorders
- Protections
- "All or substantially all" rule for antidepressants, antipsychotics, and anticonvulsants
- Fixed copay for generics, slightly higher for branded drugs, can't use cost-sharing tiers
- Risk adjusted payments to PDPs
Slide 3

Medication Use and Spending: U.S. Community Population
| % With Use | Total Spending $ | Percent Distribution of Spending by Source | |||||
|---|---|---|---|---|---|---|---|
| OOP | Medicare | Medicaid | Private | Other | |||
| 2005 | |||||||
| Antidepressants (all) | 8.5 | 13.3b | 36 | 2 | 14 | 43 | 6 |
| Antipsychotics (all) | 1.3 | 5.5b | 23 | 1 | 55 | 14 | 6 |
| Anticonvulsants | 2.7 | 5.5b | 29 | 2 | 33 | 30 | 7 |
| ALL PRESCRIPTION DRUGS | 63.1 | 213b | 39 | 3 | 14 | 37 | 7 |
| 2006 | |||||||
| Antidepressants (all) | 8.4 | 13.2b | 35 | 16* | 8* | 36* | 5 |
| Antipsychotics (all) | 1.3 | 5.7b | 26 | 21* | 26* | 20 | 7 |
| Anticonvulsants | 2.8 | 5.7b | 34 | 16* | 19* | 26 | 5 |
| ALL PRESCRIPTION DRUGS | 62.6 | 224b | 35* | 20* | 7* | 33* | 6* |
SOURCE: Medical Expenditure Panel Survey 2005-2006
Slide 4

Medication Use and Spending: Medicare Community Population
| % With Use | Total Spending $ | Percent Distribution of Spending by Source | |||||
|---|---|---|---|---|---|---|---|
| OOP | Medicare | Medicaid | Private | Other | |||
| 2005 | |||||||
| Antidepressants (all) | 16.0 | 3.8b | 41 | 8 | 18 | 23 | 10 |
| Antipsychotics (all) | 3.3 | 2.1b | 25 | 4 | 64 | 4 | 3 |
| Anticonvulsants | 7.0 | 2.1b | 29 | 4 | 35 | 22 | 9 |
| ALL PRESCRIPTION DRUGS | 91.0 | 88.5b | 43 | 7 | 16 | 23 | 11 |
| 2006 | |||||||
| Antidepressants (all) | 18.1* | 4.1b | 32* | 52* | 1* | 10* | 5 |
| Antipsychotics (all) | 3.6 | 1.9b | 22 | 61* | 6* | 4 | 7 |
| Anticonvulsants | 7.2 | 1.9b | 31 | 48* | 2* | 12 | 7 |
| ALL PRESCRIPTION DRUGS | 91.2 | 96.3b | 31* | 45* | 7* | 14* | 8* |
SOURCE: Medical Expenditure Panel Survey 2005-2006
Slide 5

Medication Use and Spending: Dual Eligible Community Population
| % With Use | Total Spending $ | Percent Distribution of Spending by Source | |||||
|---|---|---|---|---|---|---|---|
| OOP | Medicare | Medicaid | Private | Other | |||
| 2005 | |||||||
| Antidepressants (all) | 18.8 | 0.9b | 20 | 5 | 70 | 3 | 2 |
| Antipsychotics (all) | 8.5 | 1.5b | 12 | 2 | 84 | 0 | 1 |
| Anticonvulsants | 13.0 | 0.9b | 15 | 3 | 82 | 1 | 0 |
| ALL PRESCRIPTION DRUGS | 88.0 | 18.7b | 19 | 5 | 73 | 1 | 2 |
| 2006 | |||||||
| Antidepressants (all) | 20.8 | 1.0b | 9* | 84* | 5* | 0 | 3 |
| Antipsychotics (all) | 8.4 | 1.0b | 6 | 83* | 11* | 0 | 0 |
| Anticonvulsants | 11.5 | 0.6b* | 12 | 78* | 7* | 1 | 2 |
| ALL PRESCRIPTION DRUGS | 87.0 | 17.7b | 17 | 77* | 5* | 0* | 1 |
SOURCE: Medical Expenditure Panel Survey 2005-2006
Slide 6

Formulary Coverage of Selected Atypical Antipsychotics
| Drug Product | % Covered (Yes/No) | ||
|---|---|---|---|
| '06 | '07 | '08 | |
| Abilify | 100% | 100% | 100% |
| Abilify Discmelt | N/A | 83% | 100% |
| Risperdal | 100% | 100% | 100% |
| Risperdal Consta (IM) | 93% | 100% | 100% |
| Risperdal M-TAB ODT | 93% | 100% | 100% |
| Zyprexa | 100% | 100% | 100% |
| Zyprexa IM | 74% | 90% | 100% |
| Zyprexa Zydis | 84% | 100% | 100% |
SOURCE: January 2006, 2007, and 2008 CMS Prescription Drug Formulary and Pharmacy Network Files
Slide 7

Formulary Coverage of Selected Antidepressants
| Drug Product | % Covered (Yes/No) | ||
|---|---|---|---|
| '06 | '07 | '08 | |
| Celexa | 17% | 29% | 28% |
| Citalopram | 100% | 100% | 100% |
| Lexapro | 71% | 83% | 88% |
| Cymbalta | 100% | 100% | 100% |
| Paroxetine | 100% | 100% | 100% |
| Paxil | 17% | 29% | 28% |
| Paxil CR | 64% | 59% | 52% |
SOURCE: January 2006, 2007, and 2008 CMS Prescription Drug Formulary and Pharmacy Network Files
Slide 8

Use of Utilization Management Tools for Selected Atypical Antipsychotics
Of Plans that Cover Drug, % that Require Each Utilization Management Tool
| Drug Product | Prior Authorization | Step Therapy | ||||
|---|---|---|---|---|---|---|
| '06 | '07 | '08 | '06 | '07 | '08 | |
| Abilify | 14% | 14% | 12% | 0% | 5% | 7% |
| Abilify Discmelt | N/A | 16% | 18% | N/A | 5% | 7% |
| Risperdal | 11% | 0% | 0% | 0.5% | 0% | 0% |
| Risperdal Consta (IM) | 26% | 17% | 15% | 0.5% | 0% | 0% |
| Risperdal M-TAB ODT | 11% | 6% | 6% | 0.5% | 0% | 0% |
| Zyprexa | 11% | 10% | 7% | 0.5% | 3% | 7% |
| Zyprexa IM | 23% | 16% | 7% | 0.5% | 4% | 7% |
| Zyprexa Zydis | 7% | 19% | 18% | 0.5% | 0.2% | 2% |
SOURCE: January 2006, 2007, and 2008 CMS Prescription Drug Formulary and Pharmacy Network Files
Slide 9

Use of Utilization Management Tools for Selected Antidepressants
| Drug Product | Prior Authorization | Step Therapy | ||||
|---|---|---|---|---|---|---|
| '06 | '07 | '08 | '06 | '07 | '08 | |
| Celexa | 0% | 2% | 2% | 0% | 3% | 51% |
| Citalopram | 0% | 0% | 0% | 1% | 0% | 0% |
| Lexapro | 0% | 0% | 0% | 0% | 14% | 26% |
| Cymbalta | 15% | 1% | 2% | 0% | 24% | 33% |
| Paroxetine | 0% | 0% | 0% | 4% | 0% | 0% |
| Paxil | 0% | 2% | 2% | 0% | 3% | 51% |
| Paxil CR | 5% | 0% | 1% | 5% | 7% | 39% |
SOURCE: January 2006, 2007, and 2008 CMS Prescription Drug Formulary and Pharmacy Network Files
Slide 10

Percentage of Benchmark PDPs Requiring Either Step Therapy or Prior Authorization for Any Drug
2006
- Anticonvulsants: 31.8%
- Antidepressants: 25.4%
- Antipsychotics: 39.1%
2007
- Anticonvulsants: 52.0%
- Antidepressants: 41.43%
- Antipsychotics: 37.7%
2008
- Anticonvulsants: 62.2%
- Antidepressants: 50.1%
- Antipsychotics: 43.8%
SOURCE: January 2006, 2007, and 2008 CMS Prescription Drug Formulary and Pharmacy Network Files
Slide 11

Other Findings from the Literature
- Medication Discontinuities
- Some evidence of problems accessing particular medications (Hall et al 2007; West 2007, 2009)
- Psychotropic Drug Prices
- Frank and Newhouse (2008) some evidence that prices for antipsychotics increased under Part D
- Plan Choice
- Most Dual Eligibles assigned randomly, few switch plans (11% in 2006, Neuman et al. 2007)
- Reduction in the Number of Benchmark Plans
- 409 plans in 2006 ≥308 in 2009
- 2009 Six states have ≤5 plans, Nevada has 1
Slide 12

Summary and Implications: Out-of-Pocket Costs
- Major Change in Financing of Psychotropic Medications:
- Out of pocket costs decreased for non dual-eligibles
- Out of pocket costs flat for dual-eligibles
- Some indirect evidence of medication discontinuities
Slide 13

Summary and Implications: Formulary Coverage
- Formulary coverage relatively generous
- But gaps for some formulations
- Increasing use of utilization management
- Consider monitoring prior authorization approval rates, include in plan performance
- Consider alternatives to random assignment
Slide 14

Summary and Implications:
PDP Market
- PDPs exiting from market
- Limits choice
- Reassignment may lead to medication discontinuities
- Doubling of PDP risk corridors in 2008 exposes plans to greater risk and may lead to further plan exits if risk adjustment doesn't accurately reflect dual eligibles expected costs
- Consider changes in risk adjustment systems to include drug utilization
- Consider exposing PDPs to less risk for dual-eligibles
Slide 15

More Information
- Donohue, Julie M, Haiden A. Huskamp and Samuel H. Zuvekas. 2009. "Dual Eligibles with Mental Disorders and Medicare Part D: How Are They Faring?" Health Affairs 28(May/June): 746-759.


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