This information is for reference purposes only. It was current when produced and may now be outdated. Archive material is no longer maintained, and some links may not work. Persons with disabilities having difficulty accessing this information should contact us at: https://info.ahrq.gov. Let us know the nature of the problem, the Web address of what you want, and your contact information.
Please go to www.ahrq.gov for current information.
Database III: Genetic tests in development
Database of genetic tests in development
Table III-1: Test (by major types
of cancer)
Return to Contents
| Name |
Other Name |
Use |
Breast |
Prostate |
Lung |
Colorectal |
Pancreas |
Ovarian |
Esophagus |
Liver |
Lymphoma |
Leukemia |
Other |
| AFP-L3 |
|
Primary prevention |
|
|
|
|
|
|
|
x |
|
|
|
| Alpha Catenin |
Methylation marker |
Prognosis |
x |
|
|
|
|
|
|
|
|
|
|
| APC |
|
Detection |
|
|
|
x |
|
|
|
|
|
|
|
| BAT-26 |
Microsatallite instability |
Detection |
|
|
|
x |
|
|
|
|
|
|
|
| Bladder cancer test |
|
Diagnosis |
|
|
|
|
|
|
|
|
|
|
x |
| BladderChek |
NMP22 |
Diagnosis |
|
|
|
|
|
|
|
|
|
|
x |
| Breast Cancer Detection |
Nipple Aspirate Fluid |
Diagnosis |
x |
|
|
|
|
|
|
|
|
|
|
| Breast Cancer Outcome Prediction Test |
PIX2/TTF1 |
Diagnosis |
x |
|
|
|
|
|
|
|
|
|
|
| Cancer antigen 72-4 |
CA 72-4 |
Diagnosis |
|
|
|
|
|
|
|
|
|
|
x |
| CDK family |
Cyclin dependent kinase family |
Management |
|
|
x |
|
|
|
|
|
|
|
|
| CDKN24 |
Methylation marker |
Detection |
|
|
|
x |
|
|
|
|
|
|
|
| CDP/Cux |
|
Diagnosis |
x |
|
|
|
|
|
|
|
|
|
|
| CellSearch |
Circulating tumor cells |
Diagnosis |
x |
|
|
|
|
|
|
|
|
|
|
| CeMines CellCorrect Lab |
|
Diagnosis |
|
|
x |
|
|
|
|
|
|
|
|
| Chromosome 8q gain |
|
Management |
|
|
|
|
|
x |
|
|
|
|
|
| c-Kit pharmDx |
Gleevec sensitivity test |
Management |
|
|
|
|
|
|
|
|
|
|
x |
| Colorectal cancer test |
|
Diagnosis |
|
|
|
x |
|
|
|
|
|
|
|
| Colorectal gene panel |
7 gene pharmacogenomic panel |
Management |
|
|
|
x |
|
|
|
|
|
|
|
| Colorectalert |
|
Diagnosis |
|
|
|
x |
|
|
|
|
|
|
|
| Conversion Analysis |
Conversion Technology |
Diagnosis |
|
|
|
x |
|
|
|
|
|
|
|
| Cox-2 RNA |
Stool |
Detection |
|
|
|
x |
|
|
|
|
|
|
|
| cPSA |
Complexed PSA |
Management |
|
x |
|
|
|
|
|
|
|
|
|
| CupPrint |
|
Management |
|
|
|
|
|
|
|
|
|
|
x |
| Cyfra 21-1 |
Cytokeratin fragment 19 |
Diagnosis |
|
|
x |
|
|
|
|
|
|
|
|
| Cytokeratin 20 |
CK 20 |
Diagnosis |
|
|
|
x |
|
|
|
|
|
|
|
| CytoVision |
|
Diagnosis |
|
|
|
|
|
|
|
|
|
x |
|
| des-gamma carboxyprothrombin |
|
Detection |
|
|
|
|
|
|
|
x |
|
|
|
| DNA methylation |
Oncomethylome |
Detection |
|
x |
x |
|
|
x |
|
|
|
|
x |
| DNA methylation |
Second Code |
Diagnosis |
|
x |
x |
x |
|
|
|
|
|
|
|
| EEF1A2 |
Elongation factor |
Management |
x |
|
|
|
|
|
|
|
|
|
|
| EGFR |
Genzyme |
Detection |
|
|
x |
|
|
x |
|
|
|
|
x |
| EGFR |
|
Management |
|
|
x |
|
|
|
|
|
|
|
|
| EPCA |
|
Diagnosis |
|
x |
|
|
|
|
|
|
|
|
|
| eTag |
|
Management |
x |
|
x |
|
|
|
|
|
|
|
|
| Genomic Test |
3q, 7q, 16q, 17pter-q21 |
Diagnosis |
|
|
|
|
|
x |
|
|
|
|
|
| GOS |
Stool |
Detection |
|
|
|
x |
|
|
|
|
|
|
|
| GSTM1 |
|
Prediction |
|
|
x |
|
|
|
|
|
|
|
|
| GSTP1 |
|
Management |
|
x |
|
|
|
|
|
|
|
|
|
| Her-1, Her-2, Her-3, Her-4 |
|
Diagnosis |
x |
|
|
|
|
|
|
|
|
|
|
| HLA-E |
|
Prognosis |
|
|
|
|
|
|
|
|
|
|
x |
| HP1alpha |
|
Management |
x |
|
|
|
|
|
|
|
|
|
|
| HPV test |
DNA with Pap Test |
Diagnosis |
|
|
|
|
|
|
|
|
|
|
x |
| HPV test |
Human papilloma virus cell swab |
Diagnosis |
|
|
|
|
|
|
|
|
|
|
x |
| IGF-II |
|
Prediction |
|
|
|
|
|
|
|
|
|
|
x |
| IMI breast cancer test |
|
Diagnosis |
x |
|
|
|
|
|
|
|
|
|
|
| Immunocyt/ uCyt |
|
Diagnosis |
|
|
|
|
|
|
|
|
|
|
x |
| Iressa test |
|
Management |
|
|
x |
|
|
|
|
|
|
|
|
| Key2 |
|
Diagnosis |
x |
|
|
|
|
|
|
|
|
|
|
| K-ras |
|
Detection |
|
|
x |
x |
|
|
|
|
|
|
|
| Leukemia Affymetrix Chip |
|
Diagnosis |
|
|
|
|
|
|
|
|
|
x |
|
| Leukemia blood test |
MRD test |
Recurrence |
|
|
|
|
|
|
|
|
|
x |
|
| Lung cancer test |
|
Diagnosis |
|
|
x |
|
|
|
|
|
|
|
|
| Lung cancer test |
Electronic Nose |
Diagnosis |
|
|
x |
|
|
|
|
|
|
|
|
| LungAlert |
|
Diagnosis |
|
|
x |
|
|
|
|
|
|
|
|
| Lysophopholipids |
LPA |
Detection |
|
|
|
|
|
x |
|
|
|
|
|
| M2-PK |
|
Primary prevention |
|
|
|
x |
|
|
|
|
|
|
|
| MammaPrint |
|
Management |
x |
|
|
|
|
|
|
|
|
|
|
| Matrix metalloproeinases |
MMP |
Detection |
|
|
|
|
|
x |
|
|
|
|
|
| Melanoma inhibiting antigen |
MIA |
Diagnosis |
|
|
|
|
|
|
|
|
|
|
x |
| Melastatin |
mRNA expression |
Management |
|
|
|
|
|
|
|
|
|
|
x |
| MESOMARK |
|
Diagnosis |
|
|
|
|
|
|
|
|
|
|
x |
| MGMT |
Methylation marker |
Detection |
|
|
|
x |
|
|
|
|
|
|
|
| Microsatelitte Analysis |
Urine MicroSatellite Analysis |
Detection |
|
|
|
|
|
|
|
|
|
|
x |
| MLH1 |
Methylation marker |
Detection |
|
|
|
x |
|
|
|
|
|
|
|
| MN protein |
|
Detection |
|
|
|
|
|
x |
|
|
|
|
|
| MSA |
|
Management |
|
|
|
|
|
|
|
|
|
|
x |
| MSA analysis |
Microsatellite DNA |
Diagnosis |
|
|
|
|
|
|
|
|
|
|
x |
| NAF test |
|
Diagnosis |
x |
|
|
|
|
|
|
|
|
|
|
| NMP179 |
|
Diagnosis |
|
|
|
|
|
|
|
|
|
|
x |
| NMP22 |
Matritek's Bladderchek test |
Detection |
|
|
|
|
|
|
|
|
|
|
x |
| NMP35 |
|
Diagnosis |
|
|
|
x |
|
|
|
|
|
|
|
| NMP48 |
|
Diagnosis |
|
x |
|
|
|
|
|
|
|
|
|
| NMP66 |
|
Diagnosis |
x |
|
|
|
|
|
|
|
|
|
|
| OncoVue breast cancer risk test |
Tagit |
Primary prevention |
x |
|
|
|
|
|
|
|
|
|
|
| Ovacheck |
|
Diagnosis |
|
|
|
|
|
x |
|
|
|
|
|
| Ovarian cancer biomarker test |
|
Diagnosis |
|
|
|
|
|
x |
|
|
|
|
|
| Ovarian cancer test |
|
Diagnosis |
|
|
|
|
|
x |
|
|
|
|
|
| Ovarian cancer test |
Ovarian Cancer Prognostic Profile |
Management |
|
|
|
|
|
x |
|
|
|
|
|
| Ovarian pap test |
|
Detection |
|
|
|
|
|
x |
|
|
|
|
|
| p16, p15, p14 deletions |
|
Management |
|
|
|
|
|
|
|
|
|
x |
x |
| p202 |
|
Management |
|
x |
|
|
|
|
|
|
|
|
|
| p53 Affymetrix Chip |
|
Diagnosis |
x |
|
|
|
|
|
|
|
|
|
|
| Prostate 63 |
AsymmetRx |
Management |
|
x |
|
|
|
|
|
|
|
|
|
| Prostate biomarkers |
|
Management |
|
x |
|
|
|
|
|
|
|
|
|
| Prostate Cancer Blood Test |
ProteomeDx |
Diagnosis |
|
x |
|
|
|
|
|
|
|
|
|
| Protein Profile test |
Lysophosphatidic acid (LPA) |
Recurrence |
|
|
|
|
|
x |
|
|
|
|
|
| PSA testing |
In office |
Diagnosis |
|
x |
|
|
|
|
|
|
|
|
|
| PSMA |
Prostate specific membrane antigen |
Management |
|
x |
|
|
|
|
|
|
|
|
|
| PSP94 |
Prostate secratory protein |
Diagnosis |
|
x |
|
|
|
|
|
|
|
|
|
| PTEN tumor suppressor |
|
Management |
|
x |
|
|
|
|
|
|
|
|
|
| PyloriProbe |
DR70 |
Diagnosis |
|
|
|
x |
|
|
|
|
|
|
|
| Recaf |
Alpha feto protein receptor |
Diagnosis |
x |
x |
x |
x |
|
|
|
|
|
|
|
| RhoC GTPase |
|
Management |
x |
|
|
|
|
|
|
|
|
|
|
| S100 |
|
Diagnosis |
|
|
|
|
|
|
|
|
|
|
x |
| SELDI-TOF-MS |
Molecular profiling using SELDI |
Management |
x |
x |
x |
|
|
x |
|
|
|
|
|
| SurePath |
|
Diagnosis |
|
|
|
|
|
|
|
|
|
|
x |
| Telomerase |
hTR, HTerRT |
Diagnosis |
|
|
|
|
|
|
|
|
|
|
x |
| TGF genes |
|
Prognosis |
x |
|
|
|
|
|
|
|
|
|
|
| TUO test |
|
Diagnosis |
|
|
|
|
|
|
|
|
|
|
x |
| uPM3 |
PCA3 assay |
Diagnosis |
|
x |
|
|
|
|
|
|
|
|
|
| Urinary plasminogen activator |
suPAR |
Detection |
|
|
|
|
|
x |
|
|
|
|
|
| Urine test for cervical cancer |
|
Diagnosis |
|
|
|
|
|
|
|
|
|
|
x |
| VEGF |
|
Management |
|
|
|
x |
|
|
|
|
|
|
|
| WISP3 |
|
Management |
x |
|
|
|
|
|
|
|
|
|
|
Return to Contents
Proceed to Next Section