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Table 2. Overview of high-risk studies1
| Factor |
Carey(39) |
McDonald(38) |
Hauth(37) |
Morales(36) |
Vermuelen(35) |
| PTD <37 weeks, placebo |
23% |
35% |
57% |
39% |
|
| GA (wk) at treatment |
16-23 |
24 |
22-24 |
13-20 |
26 |
| Treatment |
Oral metronidazole
2 g, repeat @ 48 hr |
Oral metronidazole
400 bid, 2 d |
Oral metronidazole
250 mg tid, 7 days, plus oral erythromycin 333 mg tid, 14 d |
Oral metronidazole
250 mg tid, 7 d |
Clindamycin 2% vaginal
cream daily, 7 d |
| Second treatment |
All, 24-29 wk |
If positive test, 4
wk post-treatment |
If positive test, at
28 wk |
No second treatment |
All, 32 wk |
[1] PTD, preterm delivery; GA, gestational age.
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