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Table 1. Descriptive features and effect sizes of included studies
Study
(Jadad
40 score*) |
No.
completed/
enrolled |
Screening
methods/
Screening timing
(weeks' gestation) |
PTD
<37 weeks |
PTD
<34 weeks |
PTD
<32 weeks |
PPROM |
LBW
<2500 g |
| ARR |
(90%
CI)** |
| Average-risk
women |
| McGregor30
(3) |
129/142 |
Gram stain
+
Amsel (16 to 27) |
-0.077
(-0.169 to 0.014) |
|
|
-0.006
(-0.068 to 0.056) |
-0.092
(-0.176 to 0.008) |
| Joesoef31
(4) |
681/745 |
Gram stain
(14 to 26) |
-0.015
(-0.059 to 0.029) |
|
-0.021
(-0.044 to 0.003) |
|
-0.021
(-0.056 to 0.012) |
| McDonald38
(4) |
480/480 |
Gram stain
(16 to 26) |
|
|
|
0.0017
(-0.010 to 0.044)
|
-0.003
(-0.034 to 0.027)
|
| Carey39
(5) |
1919/1953 |
Gram stain
(16 to 23) |
0.030
(-0.021 to 0.028) |
|
0.004
(-0.008 to 0.016) |
-0.014
(-0.028 to 0.000) |
0.005
(-0.019 to 0.029) |
| High-risk
women |
| Morales36
(4) |
80/94 |
Amsel (13
to 20) |
0.263 (0.096
to 0.429) |
0.066
(-0.035 to 0.166) |
|
0.288
(0.149 to 0.427) |
0.197 (0.042
to 0.362) |
| Hauth37
(4) |
177/177 |
Amsel (<24) |
0.183 (0.052
to 0.314) |
|
|
|
|
| McDonald38
(4) |
34/34 |
Gram stain
(16 to 26) |
0.294 (0.082
to 0.507) |
0.118
(-0.061 to 0.296) |
|
0.176
(0.024 to 0.329) |
0.235 (0.005
to 0.465) |
| Carey39
(5) |
210/213 |
Gram stain
(16 to 23) |
-0.075
(-0.189 to 0.039) |
0.012
(-0.055 to 0.078) |
|
-0.036
(-0.101 to 0.030) |
-0.040
(-0.137 to 0.057) |
| Vermeulen35
(4) |
22/22 |
Gram stain
(26) |
|
0.000
(-0.202 to 0.202) |
|
|
|
*Measures
quality of randomized controlled trials on a 5-point scale.
**Negative value indicates that outcome was more common in treated group
than in controls (i.e., adverse effect of treatment).
PTD, preterm delivery; PPROM, preterm premature rupture of membranes; LBW,
low birth weight; ARR, absolute risk reduction; CI, confidence interval. |
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